Tubastatin A [CAS 1252003-15-8]
Tubastatin A [CAS 1252003-15-8]
SKU:QM-0144134-01
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Product Details
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Description
Tubastatin A is a potent and selective HDAC6 inhibitor with an IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more) . Tubastatin A also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2) .
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CAS Number
[1252003-15-8]
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Molecular Formula
C20H21N3O2
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Molecular Weight
335.4
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Smiles
O=C(NO)C1=CC=C(CN2C3=C(CN(C)CC3)C4=C2C=CC=C4)C=C1
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Target
Apoptosis; Autophagy; Beta-lactamase; HDAC
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Isoform
HDAC1; HDAC6; HDAC8
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Purity
99.07
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Solubility
DMSO : 12.5 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Tubastatin A [CAS 1252003-15-8]
Tubastatin A is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.