Tubastatin A (Hydrochloride) [CAS 1310693-92-5]
Tubastatin A (Hydrochloride) [CAS 1310693-92-5]
SKU:QM-0144133-01
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Product Details
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Description
Tubastatin A Hydrochloride (Tubastatin A HCl) is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more) . Tubastatin A Hydrochloride also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2) .
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CAS Number
[1310693-92-5]
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Molecular Formula
C20H22ClN3O2
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Molecular Weight
371.86
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Smiles
O=C(C1=CC=C(C=C1)CN2C3=C(C4=C2C=CC=C4)CN(C)CC3)NO.[H]Cl
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Target
Apoptosis; Autophagy; Beta-lactamase; HDAC
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Isoform
HDAC1; HDAC6; HDAC8
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Purity
99.31
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Solubility
DMSO : 11.67 mg/mL (ultrasonic) |H2O : 6.67 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Tubastatin A (Hydrochloride) [CAS 1310693-92-5]
Tubastatin A (Hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.