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Tubastatin A (TFA) [CAS 1239262-52-2]

Tubastatin A (TFA) [CAS 1239262-52-2]

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SKU:QM-0061979

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  • Description

    Tubastatin A (TSA) TFA is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more) . Tubastatin A TFA also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2) .

  • CAS Number

    [1239262-52-2]

  • Molecular Formula

    C22H22F3N3O4

  • Molecular Weight

    449.42

  • Smiles

    O=C(NO)C1=CC=C(CN2C3=C(CN(C)CC3)C4=C2C=CC=C4)C=C1.O=C(O)C(F)(F)F

  • Target

    Apoptosis; Autophagy; HDAC

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

  • Hazard Statement

    H302-H315-H319-H335

  • Precautions

    P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Tubastatin A (TFA) [CAS 1239262-52-2]

Tubastatin A (TFA) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.