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Tubulin/HDAC-IN-2
Tubulin/HDAC-IN-2
SKU:QM-0071874
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Quantity
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Product Details
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Description
Tubulin/HDAC-IN-2 (Compound II-19k) is a dual inhibitor of Tubulin and HDAC, with an IC50 of 0.403 μM, 0.591μM, 3.552μM, 0.459μM for HDAC1/2/3/6. Tubulin/HDAC-IN-2 blocks cell cycle arrest at G2 phase, induces cell apoptosis. Tubulin/HDAC-IN-2 inhibits the growth of hematoma and solid tumor cells, reduces tumor metastasis, and also inhibits tumor growth in a liver tumor allograft mouse model[1].
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Molecular Formula
C21H19FN2O4
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Molecular Weight
382.38
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Smiles
O=C(NO)C(F)OC1=CC(C(C2=CC(C)=NC3=CC=CC=C23)=C)=CC=C1OC
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Target
Apoptosis; HDAC; Microtubule/Tubulin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Tubulin/HDAC-IN-2
Tubulin/HDAC-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.