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Tubulin/PARP-IN-2

Tubulin/PARP-IN-2

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SKU:QM-0072860

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  • Description

    Tubulin/PARP-IN-2 (compound 14) is a dual PARP-Tubulin inhibitor. Tubulin/PARP-IN-2 inhibits PARP1, PARP2, and tubulin activity with IC50 values of 74 nM, 109 nM, and 1.4 µM, respectively. Tubulin/PARP-IN-2 induces apoptosis as well as autophagy. Tubulin/PARP-IN-2 causes cell cycle arrest at the G2/M phase[1].

  • Molecular Formula

    C19H11FO3

  • Molecular Weight

    306.29

  • Smiles

    O=C1C=C(OC2=C1C=CC(C3=COC=C3)=C2)C4=CC=C(F)C=C4

  • Target

    Apoptosis; Microtubule/Tubulin

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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Tubulin/PARP-IN-2

Tubulin/PARP-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.