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Tubulin polymerization-IN-73
Tubulin polymerization-IN-73
SKU:QM-0009426
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Product Details
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Description
Tubulin polymerization-IN-73 (Compound 37) is an inhibitor for microtubule polymerization with an IC50 of 1.8 μM. Tubulin polymerization-IN-73 arrests the cell cycle at G2/M phase, induces apoptosis in A549 cell, inhibits the proliferation of A549 WT and A549/T resistant cell with IC50 of 0.023 μM and 0.057 μM. Tubulin polymerization-IN-73 exhibits antitumor efficacy in mouse model[1].
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Molecular Formula
C23H23N3O4
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Molecular Weight
405.45
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Smiles
NC1=CC(C2=CC(C3=CC=C(C(OC)=C3OC)OC)=C4N=CNC4=C2)=CC=C1OC
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Target
Apoptosis; Microtubule/Tubulin
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Shipping Conditions
Room temperature
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Tubulin polymerization-IN-73
Tubulin polymerization-IN-73 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.