Tucidinostat [CAS 1616493-44-7]
Tucidinostat [CAS 1616493-44-7]
SKU:QM-0136340-01
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Product Details
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Description
Tucidinostat (Chidamide) is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 (IC50s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9[1].
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CAS Number
[1616493-44-7]
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Molecular Formula
C22H19FN4O2
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Molecular Weight
390.41
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Smiles
O=C(C1=CC=C(CNC(/C=C/C2=CN=CC=C2)=O)C=C1)NC(C=CC(F)=C3)=C3N
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Target
HDAC
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Isoform
HDAC1; HDAC10; HDAC11; HDAC2; HDAC3; HDAC8
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Purity
98.6
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Solubility
DMSO : 50 mg/mL (ultrasonic) |Ethanol : 1 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Tucidinostat [CAS 1616493-44-7]
Tucidinostat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.