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TX1-85-1 (Standard) [CAS 1603845-32-4]
TX1-85-1 (Standard) [CAS 1603845-32-4]
SKU:QM-0002067
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Product Details
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Description
TX1-85-1 (Standard) is the analytical standard of TX1-85-1. This product is intended for research and analytical applications. TX1-85-1 is an irreversible Her3 (ErbB3) inhibitor with an IC50 of 23 nM. TX1-85-1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP-binding site of Her3. TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling[1].
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CAS Number
[1603845-32-4]
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Molecular Formula
C32H36N8O3
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Molecular Weight
580.68
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Smiles
CC(N1CCN(C2CCC(N3N=C(C4=CC(NC(C=C)=O)=C(OC5=CC=CC=C5)C=C4)C6=C3N=CN=C6N)CC2)CC1)=O
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Target
EGFR; Reference Standards
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Shipping Conditions
Room temperature
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TX1-85-1 (Standard) [CAS 1603845-32-4]
TX1-85-1 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.