Tz-Thalidomide (Standard) [CAS 2087490-42-2]
Tz-Thalidomide (Standard) [CAS 2087490-42-2]
SKU:QM-0002385
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Product Details
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Description
Tz-Thalidomide (Standard) is the analytical standard of Tz-Thalidomide. This product is intended for research and analytical applications. Tz-Thalidomide is a tetrazine tagged Thalidomide (HY-14658) (Ligands for E3 Ligase). Tz-Thalidomide has binding affinity for BRD4, with IC50s of 46.25 μM (BRD4-1) and 62.55 μM (BRD4-2). Tz-Thalidomide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups[1].
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CAS Number
[2087490-42-2]
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Molecular Formula
C29H29N7O6
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Molecular Weight
571.58
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Smiles
O=C(CCCCCOC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1)NCC(C=C4)=CC=C4C5=NN=C(C)N=N5
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Target
Epigenetic Reader Domain; Molecular Glues; PROTACs; Reference Standards
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Shipping Conditions
Room temperature
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Tz-Thalidomide (Standard) [CAS 2087490-42-2]
Tz-Thalidomide (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.