UAA crosslinker 1 (hydrochloride) [CAS 1994331-17-7]
UAA crosslinker 1 (hydrochloride) [CAS 1994331-17-7]
SKU:QM-0137063-01
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Product Details
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Description
UAA crosslinker 1 hydrochloride is an amber codon used for non-canonical amino acids (ncAAs) incorporation. The ncAAs can be incorporated into proteins in vivo by making use of the promiscuous activity of certain wildtype and engineered aminoacyl-tRNA synthetases[1]. UAA crosslinker 1 (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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CAS Number
[1994331-17-7]
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Molecular Formula
C9H18ClN5O4
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Molecular Weight
295.72
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Smiles
N[C@@H](CCCCNC(OCCN=[N+]=[N-])=O)C(O)=O.[H]Cl
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Target
Biochemical Assay Reagents
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Concentration
10mM
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Purity
98
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Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H242
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Precautions
H242
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UAA crosslinker 1 (hydrochloride) [CAS 1994331-17-7]
UAA crosslinker 1 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.