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UCM-13369 (dihydrochloride)
UCM-13369 (dihydrochloride)
SKU:QM-0153322-01
£690.30 GBP
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Product Details
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Description
UCM-13369 (Compound 4b) is a NPM1 inhibitor. UCM-13369 downregulates the pathway associated with mutant NPM1 C+, and specifically recognizes the C-end DNA-binding domain of NPM1 C+. UCM-13369 induces apoptosis in AML cell lines and primary cells. UCM-13369 can be used for leukemia research[1].
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Molecular Formula
C25H33Cl2N3O
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Molecular Weight
462.46
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Smiles
N[C@@H]([C@@H]1CCNCC2CC2)[C@@H](C3=CC=C(OC)C=C3)CC4=C1C5=C(N4)C=CC=C5.Cl.Cl
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Target
Apoptosis
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Concentration
10mM
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Purity
99.87
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Solubility
DMSO : 200 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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UCM-13369 (dihydrochloride)
UCM-13369 (dihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.