Umbralisib (hydrochloride) (Standard) [CAS 1532533-78-0]
Umbralisib (hydrochloride) (Standard) [CAS 1532533-78-0]
SKU:QM-0004875
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Product Details
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Description
Umbralisib (hydrochloride) (Standard) is the analytical standard of Umbralisib (hydrochloride) . This product is intended for research and analytical applications. Umbralisib (TGR-1202) hydrochloride is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively. Umbralisib hydrochloride exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib hydrochloride can be used for haematological malignancies reseach[1][2][3][4].
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CAS Number
[1532533-78-0]
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Molecular Formula
C31H25ClF3N5O3
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Molecular Weight
608.01
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Smiles
O=C1C(C2=CC=CC(F)=C2)=C([C@@H](N3N=C(C4=CC=C(OC(C)C)C(F)=C4)C5=C(N)N=CN=C53)C)OC6=CC=C(F)C=C16.[H]Cl
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Target
Casein Kinase; PI3K; Reference Standards
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Shipping Conditions
Room temperature
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Umbralisib (hydrochloride) (Standard) [CAS 1532533-78-0]
Umbralisib (hydrochloride) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.