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Umibecestat [CAS 1387560-01-1]
Umibecestat [CAS 1387560-01-1]
SKU:QM-0139684-01
£318.51 GBP
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Product Details
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Description
Umibecestat (CNP520) is a beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1) inhibitor with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively[1]. Umibecestat can be used for the research of alzheimer's disease.
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CAS Number
[1387560-01-1]
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Molecular Formula
C19H15ClF7N5O2
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Molecular Weight
513.8
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Smiles
O=C(NC1=NC([C@@]2(CO[C@](C)(C(N)=N2)C(F)(F)F)C)=C(C=C1)F)C3=NC=C(C=C3Cl)C(F)(F)F
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Target
Beta-secretase
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Concentration
10mM
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Purity
99.81
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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Umibecestat [CAS 1387560-01-1]
Umibecestat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.