Upamostat [CAS 590368-25-5]
Upamostat [CAS 590368-25-5]
SKU:QM-0153826-01
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Product Details
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Description
Upamostat (WX-671), a prodrug of WX-UK1, is an orally active serine protease inhibitor. Upamostat inhibits the urokinase-type plasminogen activator (uPA) system, blocking the plasminogen activation process mediated by it, thereby suppressing the invasion, migration and metastasis of tumor cells. Upamostat can be used in the research of metastatic breast cancer and locally advanced pancreatic cancer[1].
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CAS Number
[590368-25-5]
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Molecular Formula
C32H47N5O6S
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Molecular Weight
629.81
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Smiles
O=C(N1CCN(C([C@@H](NS(=O)(C2=C(C(C)C)C=C(C(C)C)C=C2C(C)C)=O)CC3=CC=CC(C(NO)=N)=C3)=O)CC1)OCC
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Target
PAI-1; Ser/Thr Protease
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Concentration
10mM
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Purity
99.02
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Solubility
DMSO : ≥ 250 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H228, H315, H319
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Precautions
H228, H315, H319
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Upamostat [CAS 590368-25-5]
Upamostat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.