Ursodeoxycholic acid-d4 [CAS 347841-46-7]
Ursodeoxycholic acid-d4 [CAS 347841-46-7]
SKU:QM-0138131-01
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Product Details
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Description
Ursodeoxycholic acid-2,2,4,4-d4 is the deuterium labeled Ursodeoxycholic acid. Ursodeoxycholic acid is a secondary bile acid issued from the transformation of (cheno) deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection[1][2][3][4][5].
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CAS Number
[347841-46-7]
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Molecular Formula
C24H36D4O4
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Molecular Weight
396.6
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Smiles
C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@@H]3O)(C([C@H](O)C(C4)([2H])[2H])([2H])[2H])[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]
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Target
Isotope-Labeled Compounds
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Purity
99.52
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Solubility
10 mM in DMSO|DMF : ≥ 10mg/mL|DMSO : ≥ 10mg/mL|Ethanol : ≥ 1mg/mL
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Ursodeoxycholic acid-d4 [CAS 347841-46-7]
Ursodeoxycholic acid-d4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.