Usnic acid [CAS 125-46-2]
Usnic acid [CAS 125-46-2]
SKU:QM-0163015-01
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Product Details
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Description
Usnic acid is a secondary metabolite of lichens with a unique dibenzofuran skeleton. Usnic acid inhibits DNA/RNA synthesis and has antibacterial activity. Usnic acid induces cell cycle arrest and apoptosis and has anticancer activity. Usnic acid inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1. Usnic acid has antioxidant and anti-inflammatory activities by inhibiting lipid peroxidation and myeloperoxidase[1][2][3][4].
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CAS Number
[125-46-2]
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Molecular Formula
C18H16O7
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Molecular Weight
344.32
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Smiles
O=C(C1(C)C(OC2=C(C(C)=O)C(O)=C(C)C(O)=C12)=C3)C(C(C)=O)C3=O
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Target
Apoptosis; Bacterial; DNA/RNA Synthesis; Nuclear Factor of activated T Cells (NFAT)
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Purity
98.9
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Solubility
DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Usnic acid [CAS 125-46-2]
Usnic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.