Vacquinol-1 (dihydrochloride) [CAS 2309312-85-2]
Vacquinol-1 (dihydrochloride) [CAS 2309312-85-2]
SKU:QM-0155283-01
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Product Details
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Description
Vacquinol-1 (NSC13316) dihydrochloride is a MKK4-specific activator that activates MAPK pathways[1]. Vacquinol-1 dihydrochloride specifically induces human glioblastoma cell (GC) death, attenuates tumor progression and prolongs survival in a glioblastoma multiforme (GBM) mouse model[2]. Vacquinol-1 dihydrochloride also induces apoptosis in hepatocellular carcinoma (HCC) cell[3].
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CAS Number
[2309312-85-2]
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Molecular Formula
C21H23Cl3N2O
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Molecular Weight
425.78
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Smiles
OC(C1NCCCC1)C2=CC(C3=CC=C(Cl)C=C3)=NC4=CC=CC=C24.[H]Cl.[H]Cl
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Target
P38 MAPK
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Purity
99.7
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Solubility
DMSO : 25 mg/mL (ultrasonic; warming) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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Vacquinol-1 (dihydrochloride) [CAS 2309312-85-2]
Vacquinol-1 (dihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.