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Vactosertib (Hydrochloride) [CAS 1352610-25-3]

Vactosertib (Hydrochloride) [CAS 1352610-25-3]

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QM-0155616-01

£118.38 GBP
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Product Details

  • Description

    Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib Hydrochloride has potently antimetastatic activity and anticancer effect[1][2].

  • CAS Number

    [1352610-25-3]

  • Molecular Formula

    C22H19ClFN7

  • Molecular Weight

    435.88

  • Smiles

    CC1=CC=CC(C2=C(C3=CN4C(C=C3)=NC=N4)NC(CNC5=CC=CC=C5F)=N2)=N1.Cl

  • Target

    TGF-β Receptor

  • Isoform

    ALK5

  • Purity

    99.32

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C (Powder, stored under nitrogen, away from moisture)

  • Shipping Conditions

    Blue Ice

  • Hazard Statement

    H302, H315, H319

  • Precautions

    H302, H315, H319
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Variant Variant total Quantity Price Variant total
5 mgQM-0155616-01
5 mgQM-0155616-01
£118.38/ea		 £0.00
£118.38/ea £0.00
10 mM - 1 mLQM-0155616-02
10 mM - 1 mLQM-0155616-02
£127.38/ea		 £0.00
£127.38/ea £0.00
10 mgQM-0155616-03
10 mgQM-0155616-03
£200.66/ea		 £0.00
£200.66/ea £0.00
25 mgQM-0155616-04
25 mgQM-0155616-04
£301.50/ea		 £0.00
£301.50/ea £0.00
50 mgQM-0155616-05
50 mgQM-0155616-05
£438.80/ea		 £0.00
£438.80/ea £0.00
100 mgQM-0155616-06
100 mgQM-0155616-06
£652.64/ea		 £0.00
£652.64/ea £0.00
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Vactosertib (Hydrochloride) [CAS 1352610-25-3]

Vactosertib (Hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.