Valproic acid-d14 (sodium)
Valproic acid-d14 (sodium)
SKU:QM-0057552
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Product Details
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Description
Valproic acid-d14 (sodium) is deuterium labeled Valproic acid (sodium) . Valproic acid sodium salt (Sodium Valproate) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium salt activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.
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Molecular Formula
C8HD14NaO2
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Molecular Weight
180.28
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Smiles
[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C(C(O[Na])=O)C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]
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Target
Autophagy; Endogenous Metabolite; HDAC; HIV; Isotope-Labeled Compounds; Mitophagy; Notch
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Purity
96.45
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Solubility
10 mM in DMSO
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H361
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Precautions
H302, H361
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Valproic acid-d14 (sodium)
Valproic acid-d14 (sodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.