Valproic acid-d4-1 [CAS 345909-03-7]
Valproic acid-d4-1 [CAS 345909-03-7]
SKU:QM-0112005
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Product Details
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Description
Valproic acid-d4-1 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches[1][2].
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CAS Number
[345909-03-7]
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Molecular Formula
C8H12D4O2
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Molecular Weight
148.24
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Smiles
CC([2H])([2H])CC(C(O)=O)CC([2H])([2H])C
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Target
Autophagy; Endogenous Metabolite; HDAC; HIV; Isotope-Labeled Compounds; Mitophagy; Notch
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Purity
99.5
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H360
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Precautions
H302, H315, H319, H360
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Valproic acid-d4-1 [CAS 345909-03-7]
Valproic acid-d4-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.