Valproic acid-d4 (sodium)
Valproic acid-d4 (sodium)
SKU:QM-0112004-01
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Product Details
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Description
Valproic acid-d4 (sodium) is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.
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Molecular Formula
C8H11D4NaO2
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Molecular Weight
170.22
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Smiles
CCC([2H])([2H])C(C([2H])([2H])CC)C(O[Na])=O
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Target
Autophagy; Endogenous Metabolite; HDAC; HIV; Isotope-Labeled Compounds; Mitophagy; Notch
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Valproic acid-d4 (sodium)
Valproic acid-d4 (sodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.