Vandetanib (Standard) [CAS 443913-73-3]
Vandetanib (Standard) [CAS 443913-73-3]
SKU:QM-0081903-01
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Product Details
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Description
Vandetanib (Standard) is the analytical standard of Vandetanib. This product is intended for research and analytical applications. Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM) . Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM) [1].
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CAS Number
[443913-73-3]
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Molecular Formula
C22H24BrFN4O2
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Molecular Weight
475.35
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Smiles
FC1=CC(Br)=CC=C1NC2=NC=NC3=CC(OCC4CCN(CC4)C)=C(C=C23)OC
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Target
Apoptosis; Autophagy; Reference Standards; VEGFR
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335-H360-H373-H400-H410
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Precautions
P260-P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P391-P403+P233-P405-P501
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Vandetanib (Standard) [CAS 443913-73-3]
Vandetanib (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.