Vardenafil (hydrochloride trihydrate) (Standard) [CAS 330808-88-3]
Vardenafil (hydrochloride trihydrate) (Standard) [CAS 330808-88-3]
SKU:QM-0107661
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Product Details
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Description
Vardenafil (hydrochloride trihydrate) (Standard) is the analytical standard of Vardenafil (hydrochloride trihydrate) . This product is intended for research and analytical applications. Vardenafil hydrochloride trihydrate is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil hydrochloride trihydrate shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4[1]. Vardenafil hydrochloride trihydrate competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels[2]. Vardenafil hydrochloride trihydrate can be used for the research of erectile dysfunction, hepatitis, diabetes[1]-[6].
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CAS Number
[330808-88-3]
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Molecular Formula
C23H39ClN6O7S
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Molecular Weight
579.11
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Smiles
O=C1N=C(C2=CC(S(=O)(N3CCN(CC)CC3)=O)=CC=C2OCC)NN4C1=C(C)N=C4CCC.Cl.O.O.O
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Target
Endogenous Metabolite; Phosphodiesterase (PDE) ; Reference Standards
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Shipping Conditions
Room temperature
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Vardenafil (hydrochloride trihydrate) (Standard) [CAS 330808-88-3]
Vardenafil (hydrochloride trihydrate) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.