Vardenafil (Standard) [CAS 224785-90-4]
Vardenafil (Standard) [CAS 224785-90-4]
SKU:QM-0108450-01
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Product Details
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Description
Vardenafil (Standard) is the analytical standard of Vardenafil. This product is intended for research and analytical applications. Vardenafil is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4[1]. Vardenafil competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels[2]. Vardenafil can be used for the research of erectile dysfunction, hepatitis, diabetes[1]-[6].
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CAS Number
[224785-90-4]
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Molecular Formula
C23H32N6O4S
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Molecular Weight
488.6
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Smiles
CCCC1=NC(C)=C2N1N=C(C(C=C(S(=O)(N3CCN(CC)CC3)=O)C=C4)=C4OCC)NC2=O
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Target
Endogenous Metabolite; Phosphodiesterase (PDE) ; Reference Standards
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Shipping Conditions
Room temperature
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Vardenafil (Standard) [CAS 224785-90-4]
Vardenafil (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.