Varenicline-13C15N [CAS 2140265-12-7]
Varenicline-13C15N [CAS 2140265-12-7]
SKU:QM-0001717
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Product Details
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Description
Varenicline-13C15N (CP 526555-13C15N) is 13C and 15N labeled Varenicline. Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α7β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation[1][2][3][4][5].
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CAS Number
[2140265-12-7]
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Molecular Formula
C11 13C2H11N 15N2
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Molecular Weight
213.22
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Smiles
C12=CC3=C(C4CNCC3C4)C=C1[15N]=[13C][13C]=[15N]2
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Target
Isotope-Labeled Compounds; nAChR
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Shipping Conditions
Room temperature
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Varenicline-13C15N [CAS 2140265-12-7]
Varenicline-13C15N is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.