Varenicline (dihydrochloride) (Standard) [CAS 866823-63-4]
Varenicline (dihydrochloride) (Standard) [CAS 866823-63-4]
SKU:QM-0001715
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Product Details
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Description
Varenicline (dihydrochloride) (Standard) is the analytical standard of Varenicline (dihydrochloride) . This product is intended for research and analytical applications. Varenicline (CP 526555-18) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α7β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation[1][2][3][4][5].
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CAS Number
[866823-63-4]
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Molecular Formula
C13H15Cl2N3
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Molecular Weight
284.18
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Smiles
[H]Cl.[H]Cl.C1(C2)CNCC2C3=CC4=NC=CN=C4C=C13
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Target
NAChR; Reference Standards
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Shipping Conditions
Room temperature
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Varenicline (dihydrochloride) (Standard) [CAS 866823-63-4]
Varenicline (dihydrochloride) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.