Varenicline (Standard) [CAS 249296-44-4]
Varenicline (Standard) [CAS 249296-44-4]
SKU:QM-0001716-01
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Product Details
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Description
Varenicline (Standard) is the analytical standard of Varenicline. This product is intended for research and analytical applications. Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α7β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation[1][2][3][4][5].
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CAS Number
[249296-44-4]
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Molecular Formula
C13H13N3
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Molecular Weight
211.27
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Smiles
C12=C(C=C3N=CC=NC3=C2)C4CC1CNC4
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Target
NAChR; Reference Standards
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Shipping Conditions
Room temperature
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Varenicline (Standard) [CAS 249296-44-4]
Varenicline (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.