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VEGFR-2/AURKA-IN-1
VEGFR-2/AURKA-IN-1
SKU:QM-0071827
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Product Details
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Description
VEGFR-2/AURKA-IN-1 (compound 5e) is a thiazolidin-4-one derivative with antiglioma activity (IC50: 6.43 μM, LN229) . VEGFR-2/AURKA-IN-1 has affinity for AURKA and VEGFR-2 and is a potential ligand. VEGFR-2/AURKA-IN-1 causes DNA strand breaks and exhibits cytotoxic and anticancer potential[1].
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Molecular Formula
C20H15ClF6N2O4S
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Molecular Weight
528.85
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Smiles
FC(F)(F)COC1=C(C(NN2C(C3=CC=C(Cl)C=C3)SCC2=O)=O)C=C(OCC(F)(F)F)C=C1
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Target
Aurora Kinase; VEGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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VEGFR-2/AURKA-IN-1
VEGFR-2/AURKA-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.