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VEGFR-2/AURKA-IN-1

VEGFR-2/AURKA-IN-1

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SKU:QM-0071827

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  • Description

    VEGFR-2/AURKA-IN-1 (compound 5e) is a thiazolidin-4-one derivative with antiglioma activity (IC50: 6.43 μM, LN229) . VEGFR-2/AURKA-IN-1 has affinity for AURKA and VEGFR-2 and is a potential ligand. VEGFR-2/AURKA-IN-1 causes DNA strand breaks and exhibits cytotoxic and anticancer potential[1].

  • Molecular Formula

    C20H15ClF6N2O4S

  • Molecular Weight

    528.85

  • Smiles

    FC(F)(F)COC1=C(C(NN2C(C3=CC=C(Cl)C=C3)SCC2=O)=O)C=C(OCC(F)(F)F)C=C1

  • Target

    Aurora Kinase; VEGFR

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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VEGFR-2/AURKA-IN-1

VEGFR-2/AURKA-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.