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VEGFR-2/BRAF-IN-2
VEGFR-2/BRAF-IN-2
SKU:QM-0066920
Price on request
Quantity
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Product Details
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Description
VEGFR-2/BRAF-IN-2 (Compound 4a) is a dual VEGFR-2 and BRAF kinases inhibitor with IC50 values of 0.111, 0.089 and 0.071 µM against VEGFR-2, BRAFV600E and BRAFWT, respectively. VEGFR-2/BRAF-IN-2 induces apoptosis and arrests the cell cycle mainly in the G1 phase[1].
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Molecular Formula
C26H21ClF3N5O3S2
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Molecular Weight
608.05
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Smiles
FC(F)(F)C1=CC=CC(NC(NNC(CSC2=NC3=C(C4=C(S3)CCCC4)C(N2C5=CC=C(C=C5)Cl)=O)=O)=O)=C1
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Target
Apoptosis; Raf; VEGFR
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Isoform
B-Raf; VEGFR2/KDR/Flk-1
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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VEGFR-2/BRAF-IN-2
VEGFR-2/BRAF-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.