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VEGFR-2-IN-12
VEGFR-2-IN-12
SKU:QM-0066422
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Product Details
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Description
VEGFR-2-IN-12 (compound 6g), a 2-oxoquinoxalinyl-1,2,4-triazole, is a potent VEGFR-2 inhibitor with an IC50 of 0.037 µM. VEGFR-2-IN-12 shows high growth inhibition against MCF-7 cells (GI50=1.6 µM) . VEGFR-2-IN-12 has antitumor activity[1].
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Molecular Formula
C22H24N6O3S
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Molecular Weight
452.53
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Smiles
COC1=CC=C(C=C1)NC(CSC2NN=C(N2C)CN3C(C(C)=NC4=CC=CC=C43)=O)=O
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Target
VEGFR
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Isoform
VEGFR2/KDR/Flk-1
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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VEGFR-2-IN-12
VEGFR-2-IN-12 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.