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VEGFR-2-IN-23 [CAS 2411174-53-1]

VEGFR-2-IN-23 [CAS 2411174-53-1]

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SKU:QM-0068113

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  • Description

    VEGFR-2-IN-23 (compound 11b) is a potent and selective VEGFR-2 inhibitor with an IC50 value of 0.34 nM. VEGFR-2-IN-23 shows antitumor activity. VEGFR-2-IN-23 induces apoptosis and cell cycle arrest at G1 phase[1].

  • CAS Number

    [2411174-53-1]

  • Molecular Formula

    C22H15N5O2

  • Molecular Weight

    381.39

  • Smiles

    N#CC1=C(N=C(C=C1C2=CC=C(C=C2)[N+]([O-])=O)C3=CC4=CC=CC=C4C=C3)NN

  • Target

    Apoptosis; MDM-2/p53; VEGFR

  • Isoform

    VEGFR2/KDR/Flk-1

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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VEGFR-2-IN-23 [CAS 2411174-53-1]

VEGFR-2-IN-23 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.