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VEGFR-2-IN-36
VEGFR-2-IN-36
SKU:QM-0071658
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Quantity
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Product Details
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Description
VEGFR-2-IN-36 (compound 15) is a VEGFR-2 inhibitor (IC50: 0.067 μM) and inducer of apoptosis with anticancer activity. VEGFR-2-IN-36 upregulates BAX levels and downregulates Bcl-2 levels. VEGFR-2-IN-36 is toxic to cancer cells, MCF-7 (IC50=0.42 μM) and HepG2 (IC50=0.22 μM) [1].
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Molecular Formula
C24H23N7O5
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Molecular Weight
489.48
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Smiles
CN(C=N1)C2=C1N(C)C(N(CC(NC3=CC=C(/C(C)=N/NC(C4=CC=C(O)C=C4)=O)C=C3)=O)C2=O)=O
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Target
Apoptosis; Bcl-2 Family; VEGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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VEGFR-2-IN-36
VEGFR-2-IN-36 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.