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VEGFR-2-IN-47
VEGFR-2-IN-47
SKU:QM-0131382
Price on request
Quantity
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Product Details
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Description
VEGFR-2-IN-47 (compound 7g) is a potent VEGFR-2 inhibitor with an IC50 value of 0.072 µM. VEGFR-2-IN-47 can induce G2 / M phase cell cycle arrest, promote apoptosis, and boost immunomodulation by downregulating TNF-α expression and upregulating IL-2 levels in MCF-7 cells. VEGFR-2-IN-47 has the potential to be used for the research of cancer such as breast cancer and liver carcinoma [1].
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Molecular Formula
C23H22N6O4
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Molecular Weight
446.46
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Smiles
CC1=CC=CC(NC(C2=CC=C(C=C2)NC(CN3C(C4=C(N(C3=O)C)N=CN4C)=O)=O)=O)=C1
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Target
VEGFR
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Isoform
VEGFR2/KDR/Flk-1
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Shipping Conditions
Room temperature
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VEGFR-2-IN-47
VEGFR-2-IN-47 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.