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VEGFR-2-IN-53
VEGFR-2-IN-53
SKU:QM-0082452
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Product Details
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Description
VEGFR-2-IN-53 (Compound 15w) is a VEGFR-2 inhibitor with an IC50 of 4.34 μM. VEGFR-2-IN-53 induces apoptosis by inhibiting VEGFR-2 activity and preventing cell migration, thereby exhibiting anti-angiogenic effects. The IC50 value of VEGFR-2-IN-53 for inhibiting MCF-7 cell growth is 3.87 μM. VEGFR-2-IN-53 can be used in cancer research[1].
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Molecular Formula
C29H23N5O2S
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Molecular Weight
505.59
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Smiles
O=C(NC1=NC2=C(C=CC=C2)S1)[C@H]3[C@H](C4=C(C)N(C5=CC=CC=C5)N=C4C)[C@@](C6=CC=CC=C6N7)3C7=O
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Target
Apoptosis; VEGFR
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Isoform
VEGFR2/KDR/Flk-1
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Shipping Conditions
Room temperature
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VEGFR-2-IN-53
VEGFR-2-IN-53 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.