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VEGFR-2-IN-66
VEGFR-2-IN-66
SKU:QM-0011330
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Product Details
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Description
VEGFR-2-IN-66 (Compound 6) is an orally active VEGFR-2 inhibitor with an IC50 value of 0.509 µM and an IC50 value of 7.48 μM for inhibiting the proliferation of MCF-7 cells. VEGFR-2-IN-66 exerts its anti-cancer activity by arresting the cell cycle, inducing apoptosis, and regulating gene expression, and can be used in the research of the breast cancer field[1].
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Molecular Formula
C20H22N8O3
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Molecular Weight
422.44
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Smiles
O=C(NC1CCC(NC1=O)=O)CN(CC2)CCN2C3=NC4=CC=CC=C4C5=NN=CN35
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Target
Apoptosis; VEGFR
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Isoform
VEGFR2/KDR/Flk-1
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Shipping Conditions
Room temperature
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VEGFR-2-IN-66
VEGFR-2-IN-66 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.