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VEGFR-2-IN-69
VEGFR-2-IN-69
SKU:QM-0014063
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Product Details
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Description
VEGFR-2-IN-69 (Compound 5A) is a dual inhibitor of VEGFR-2 and Telomerase, which upregulates the expression of caspase 3, caspase 8 and caspase 9, while downregulating CDK-2, CDK-4 and CDK-6. VEGFR-2-IN-69 exhibits an IC50 of 15.46 µM against HCT116 cells[1].
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Molecular Formula
C18H16ClN5O
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Molecular Weight
353.81
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Smiles
CC1=C(N=NN1C2=CC=C(C=C2)Cl)C(N/N=C(C3=CC=CC=C3)\C)=O
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Target
Caspase; CDK; Telomerase; VEGFR
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Isoform
Caspase 3; Caspase 8; Caspase 9; CDK2; CDK4; CDK6
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Shipping Conditions
Room temperature
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VEGFR-2-IN-69
VEGFR-2-IN-69 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.