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VEGFR-2-IN-70
VEGFR-2-IN-70
SKU:QM-0012771
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Quantity
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Product Details
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Description
VEGFR-2-IN-70 is a potent VEGFR-2 inhibitor with an IC50 of 18.04 nM. VEGFR-2-IN-70 exhibits cytotoxicity against A549 and MCF-7 cancer cells with IC50 values of 0.43 μM and 3.8 μM, respectively. VEGFR-2-IN-70 induces G1 cell cycle arrest and apoptosis in lung cancer cells. VEGFR-2-IN-70 is useful in cancer research[1].
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Molecular Formula
C20H17ClN6O2S
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Molecular Weight
440.91
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Smiles
CC1=C(C(NNC(NC2=C(C)N(C3=CC=C(Cl)C=C3)N=N2)=O)=O)SC4=C1C=CC=C4
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Target
Apoptosis; Bcl-2 Family; Caspase; MDM-2/p53; VEGFR
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Isoform
Bax; Caspase 3; Caspase 8; Caspase 9; VEGFR2/KDR/Flk-1
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Shipping Conditions
Room temperature
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VEGFR-2-IN-70
VEGFR-2-IN-70 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.