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VEGFR-2-IN-71

VEGFR-2-IN-71

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SKU:QM-0012770

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  • Description

    VEGFR-2-IN-71 is a dual VEGFR2/tubulin inhibitor. VEGFR-2-IN-71 inhibits tumor cell proliferation and induces apoptosis and cell cycle arrest. VEGFR-2-IN-71 inhibits angiogenesis in the chick chorioallantoic membrane (CAM) model. VEGFR-2-IN-71 inhibits tumor growth in the HGC-27 xenograft model by inhibiting VEGFR2 and tubulin. VEGFR-2-IN-71 has low oral bioavailability in rats. VEGFR-2-IN-71 can be used in cancer research[1].

  • Molecular Formula

    C26H20F4N2O6

  • Molecular Weight

    532.44

  • Smiles

    COC1=C(OC)C(OC)=C(C(C=C(C2=CC=C(NC(NC3=CC=C(F)C(C(F)(F)F)=C3)=O)C=C2)O4)=O)C4=C1

  • Target

    Apoptosis; Microtubule/Tubulin; VEGFR

  • Shipping Conditions

    Room temperature

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VEGFR-2-IN-71

VEGFR-2-IN-71 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.