VEGFR-2-IN-73
VEGFR-2-IN-73
SKU:QM-0014910
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Product Details
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Description
VEGFR-2-IN-73 is a potent and selective VEGFR-2 inhibitor, showing selectively inhibition of VEGFR-2 (IC50 = 0.0787 μM) over EGFR (IC50 = 1.31 μM) . VEGFR-2-IN-73 demonstrates potent antiproliferative activity across multiple cancer cell lines. VEGFR-2-IN-73 induces G2/M and Pre-G1 phase arrest and significantly enhances apoptosis. VEGFR-2-IN-73 can be used in cancer research, such as colorectal carcinoma, hepatocellular carcinoma, and breast cancer[1].
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Molecular Formula
C29H29N5O3S2
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Molecular Weight
559.7
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Smiles
C/C(C1=CC=C(C=C1)S(=O)(N2CCC(CC2)C)=O)=N/N=C3SC(C(C4=CC=CC=C4)=O)=NN\3C5=CC=CC=C5
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Target
Apoptosis; VEGFR
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Isoform
VEGFR2/KDR/Flk-1
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Shipping Conditions
Room temperature
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VEGFR-2-IN-73
VEGFR-2-IN-73 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.