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VEGFR-2-IN-74
VEGFR-2-IN-74
SKU:QM-0015227
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Product Details
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Description
VEGFR-2-IN-74 (compound 55) is a potent VEGFR-2 inhibitor (IC50 = 0.035 µM) . VEGFR-2-IN-74 exhibits good anti proliferative activity and can induce apoptosis in various cancer cells, such as A549 (IC50 = 2.67 µM) and HCT116 (IC50 = 10.87 µM) cells. VEGFR-2-IN-74 has low toxicity to normal cells. VEGFR-2-IN-74 shows significant anti angiogenic effects in chicken embryo models. VEGFR-2-IN-74 can be used in the research of cancer[1].
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Molecular Formula
C25H27N5O4
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Molecular Weight
461.51
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Smiles
O=C(NC)C1=CC=C(OCC2=CC=C(NC(NC(N3)=NC(C)C4=C3CCCC4=O)=O)C=C2)C=C1
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Target
Apoptosis; VEGFR
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Isoform
VEGFR2/KDR/Flk-1
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Shipping Conditions
Room temperature
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VEGFR-2-IN-74
VEGFR-2-IN-74 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.