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VEGFR-2/STAT-3-IN-1
VEGFR-2/STAT-3-IN-1
SKU:QM-0094745
Price on request
Quantity
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Product Details
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Description
VEGFR-2/STAT-3-IN-1 (Compound 9f) is a dual inhibitor for VEGFR-2 (IC50=26.3 nM) and STAT-3 (IC50=5.63 nM) . VEGFR-2/STAT-3-IN-1 inhibits the proliferation of cancer cells PANC1 and PC3 with IC50 of 0.14 and 0.10 µM. VEGFR-2/STAT-3-IN-1 induces apoptosis in PC3[1].
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Molecular Formula
C26H20N6O4
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Molecular Weight
480.47
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Smiles
O=C(N1C(C2=CC=CC=C2)=O)/C(C3=C1C=CC=C3)=N\NC(C4=C(C)N(C5=CC=C(OC)C=C5)N=N4)=O
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Target
STAT; VEGFR
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Isoform
STAT3; VEGFR2/KDR/Flk-1
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Shipping Conditions
Room temperature
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VEGFR-2/STAT-3-IN-1
VEGFR-2/STAT-3-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.