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VEGFR-IN-5
VEGFR-IN-5
SKU:QM-0100488
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Product Details
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Description
VEGFR-IN-5 (compound 9k) is a potent inhibitor of VEGFR2, with the IC50 of 8.4 nM and an acceptable oral bioavailability. VEGFR-IN-5 inhibits migration and invasion of human umbilical vein endothelial cells (HUVEC) cells and induces apoptosis[1].
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Molecular Formula
C31H28ClF3N6O2
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Molecular Weight
609.04
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Smiles
COC1=CC2=CC=C(C=C2C=C1C(NC3=CC=C(C(C(F)(F)F)=C3)CN4CCN(CC4)C)=O)C5=CN=C6C=CC(Cl)=NN56
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Target
VEGFR
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Isoform
VEGFR2/KDR/Flk-1
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Shipping Conditions
Room temperature
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VEGFR-IN-5
VEGFR-IN-5 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.