Vercirnon (sodium) (Standard) [CAS 886214-18-2]
Vercirnon (sodium) (Standard) [CAS 886214-18-2]
SKU:QM-0007775-01
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Product Details
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Description
Vercirnon (sodium) (Standard) is the analytical standard of Vercirnon (sodium) . This product is intended for research and analytical applications. Vercirnon (GSK1605786A) sodium is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon sodium inhibits CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon sodium is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 μM for all) . Vercirnon sodium is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively[1].
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CAS Number
[886214-18-2]
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Molecular Formula
C22H20ClN2NaO4S
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Molecular Weight
466.91
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Smiles
O=S(C1=CC=C(C(C)(C)C)C=C1)([N-]C2=CC=C(Cl)C=C2C(C3=CC=[N+]([O-])C=C3)=O)=O.[Na+]
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Target
CCR; Reference Standards
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Shipping Conditions
Room temperature
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Vercirnon (sodium) (Standard) [CAS 886214-18-2]
Vercirnon (sodium) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.