Verosudil (hydrochloride) [CAS 1414854-44-6]
Verosudil (hydrochloride) [CAS 1414854-44-6]
SKU:QM-0088287
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Product Details
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Description
Verosudil (AR-12286) hydrochloride is the hydrochloride form of Verosudil. Verosudil hydrochloride is a ROCK inhibitor. Verosudil hydrochloride has equal inhibitory activity against ROCK1 and ROCK2 (Ki: 2 nM). Verosudil hydrochloride is less selective for PKA, PKCT, MRCKA, and CAM2A (Ki: 69 nM, 9322 nM, 28 nM, 5855 nM, respectively). Verosudil hydrochloride increases trabecular outflow capacity to reduce intraocular pressure. Verosudil hydrochloride is useful in the study of glaucoma and ocular hypertension[1][2].
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CAS Number
[1414854-44-6]
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Molecular Formula
C17H18ClN3O2S
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Molecular Weight
363.86
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Smiles
O=C(C(C1=CSC=C1)N(C)C)NC2=CC3=C(C=C2)C(NC=C3)=O.Cl
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Target
ROCK
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Isoform
ROCK1; ROCK2
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Shipping Conditions
Room temperature
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Verosudil (hydrochloride) [CAS 1414854-44-6]
Verosudil (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.