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VH-298 (Standard) [CAS 2097381-85-4]
VH-298 (Standard) [CAS 2097381-85-4]
SKU:QM-0002115
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Product Details
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Description
VH-298 (Standard) is the analytical standard of VH-298. This product is intended for research and analytical applications. VH-298 is a highly potent inhibitor of the VHL:HIF-α interaction with a Kd value of 80 to 90 nM. VH-298 leads to HIF-α accumulation inside HeLa cells. VH-298 is an E3 ligase Ligand, and can be used for synthesis of PROTACs[1].
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CAS Number
[2097381-85-4]
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Molecular Formula
C27H33N5O4S
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Molecular Weight
523.65
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Smiles
O=C([C@H]1N(C([C@H](C(C)(C)C)NC(C2(CC2)C#N)=O)=O)C[C@H](O)C1)NCC3=CC=C(C4=C(C)N=CS4)C=C3
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Target
HIF/HIF Prolyl-Hydroxylase; Ligands for E3 Ligase; Reference Standards
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Shipping Conditions
Room temperature
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VH-298 (Standard) [CAS 2097381-85-4]
VH-298 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.