Vonoprazan-d3 (fumarate)
Vonoprazan-d3 (fumarate)
SKU:QM-0189133
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Product Details
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Description
Vonoprazan-d3 fumarate is the deuterium labeled Vonoprazan fumarate. Vonoprazan Fumarate (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan Fumarate inhibits H+, K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease[1][2].
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Molecular Formula
C21H17D3FN3O6S
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Molecular Weight
464.48
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Smiles
OC(/C=C/C(O)=O)=O.O=S(N1C(C2=C(C=CC=C2)F)=CC(CNC([2H])([2H])[2H])=C1)(C3=CN=CC=C3)=O
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Target
Isotope-Labeled Compounds
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Vonoprazan-d3 (fumarate)
Vonoprazan-d3 (fumarate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.