Vonoprazan (Fumarate) [CAS 881681-01-2]
Vonoprazan (Fumarate) [CAS 881681-01-2]
SKU:QM-0150936-01
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Product Details
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Description
Vonoprazan Fumarate (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan Fumarate inhibits H+, K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease[1][2].
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CAS Number
[881681-01-2]
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Molecular Formula
C21H20FN3O6S
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Molecular Weight
461.46
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Smiles
O=C(O)/C=C/C(O)=O.O=S(N1C=C(CNC)C=C1C2=CC=CC=C2F)(C3=CC=CN=C3)=O
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Target
Proton Pump
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Purity
99.94
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Solubility
DMSO : 50 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Vonoprazan (Fumarate) [CAS 881681-01-2]
Vonoprazan (Fumarate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.