Vonoprazan (hydrochloride) [CAS 1957202-44-6]
Vonoprazan (hydrochloride) [CAS 1957202-44-6]
SKU:QM-0056840
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Product Details
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Description
Vonoprazan hydrochloride, a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan hydrochloride inhibits H+, K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan hydrochloride is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan hydrochloride can be used for eradication of Helicobacter pylori[1][2][3].
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CAS Number
[1957202-44-6]
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Molecular Formula
C17H17ClFN3O2S
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Molecular Weight
381.85
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Smiles
O=S(C1=CC=CN=C1)(N2C=C(CNC)C=C2C3=C(F)C=CC=C3)=O.Cl
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Target
Bacterial; Proton Pump
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Vonoprazan (hydrochloride) [CAS 1957202-44-6]
Vonoprazan (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.