Vorinostat-d5 [CAS 1132749-48-4]
Vorinostat-d5 [CAS 1132749-48-4]
SKU:QM-0059014
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Product Details
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Description
Vorinostat-d5 (SAHA-d5) is the deuterium labeled Vorinostat. Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis[1][4]. Vorinostat is also an effective inhibitor of human papillomaviruse (HPV) -18 DNA amplification[7].
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CAS Number
[1132749-48-4]
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Molecular Formula
C14H15D5N2O3
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Molecular Weight
269.35
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Smiles
O=C(NO)CCCCCCC(NC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O
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Target
Apoptosis; Autophagy; Filovirus; HDAC; HPV; Mitophagy
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Purity
99
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Hazard Statement
H319
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Precautions
P264-P280-P305+P351+P338
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Vorinostat-d5 [CAS 1132749-48-4]
Vorinostat-d5 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.