VP3.15 (dihydrobromide) [CAS 1281681-33-1]
VP3.15 (dihydrobromide) [CAS 1281681-33-1]
SKU:QM-0142682-01
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Product Details
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Description
VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE) 7- glycogen synthase kinase (GSK) 3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 dihydrobromide has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS) [1].
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CAS Number
[1281681-33-1]
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Molecular Formula
C20H24Br2N4OS
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Molecular Weight
528.3
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Smiles
[H]Br.[H]Br.N1(CC/N=C2N=C(C3=CC=CC=C3)N(C4=CC=CC=C4)S/2)CCOCC1
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Target
GSK-3; Phosphodiesterase (PDE)
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Isoform
PDE7
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Purity
98.01
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Solubility
DMSO : 62.5 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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VP3.15 (dihydrobromide) [CAS 1281681-33-1]
VP3.15 (dihydrobromide) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.